FIP200 antibody (C-Term)

Catalog No. ABIN928362

Product Details anti-FIP200 Antibody

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Chicken, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FIP200 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Chicken, Dog (Canine)

Purification: Purified

Immunogen: RB1 CC1 antibody was raised in rabbit using the C terminal of RB1 C1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RB1CC1 Blocking Peptide, catalog no. 33R-8445, is also available for use as a blocking control in assays to test for specificity of this RB1CC1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for FIP200

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Alternative Name: RB1CC1 (RB1CC1 Products)

Synonyms: DKFZp459E2330 antibody, CC1 antibody, FIP200 antibody, 2900055E04Rik antibody, 5930404L04Rik antibody, Cc1 antibody, LaXp180 antibody, RB1 inducible coiled-coil 1 antibody, RB1 inducible coiled-coil 1 L homeolog antibody, RB1-inducible coiled-coil 1 antibody, RB1CC1 antibody, rb1cc1.L antibody, rb1cc1 antibody, Rb1cc1 antibody

Background: RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene. Synonyms: Polyclonal RB1CC1 antibody, Anti-RB1CC1 antibody, RB1-inducible coiled-coil 1 antibody, CC1 antibody, DRAGOU14 antibody, FIP200 antibody.

Pathways: Regulation of Cell Size, Autophagy