SPACA1 antibody (N-Term)
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- Target See all SPACA1 Antibodies
- SPACA1 (Sperm Acrosome Associated 1 (SPACA1))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPACA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogen
- SPACA1 antibody was raised in rabbit using the N terminal of SPACA1 as the immunogen
- Top Product
- Discover our top product SPACA1 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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SPACA1 Blocking Peptide, catalog no. 33R-9051, is also available for use as a blocking control in assays to test for specificity of this SPACA1 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- SPACA1 (Sperm Acrosome Associated 1 (SPACA1))
- Alternative Name
- SPACA1 (SPACA1 Products)
- Synonyms
- SAMP32 antibody, 1700124L11Rik antibody, 4930540L03Rik antibody, sperm acrosome associated 1 antibody, SPACA1 antibody, Spaca1 antibody
- Background
- The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. Synonyms: Polyclonal SPACA1 antibody, Anti-SPACA1 antibody, sperm acrosome associated 1 antibody, MGC32952 antibody, SAMP32 antibody.
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