BMP10 antibody (N-Term)

Catalog No. ABIN928124

Product Details anti-BMP10 Antibody

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Binding Specificity: N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP10 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus)

Purification: Purified

Immunogen: Bmp10 antibody was raised in rabbit using the N terminal of Bmp10 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

Bmp10 Blocking Peptide, catalog no. 33R-4366, is also available for use as a blocking control in assays to test for specificity of this Bmp10 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for BMP10

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Alternative Name: Bmp10 (BMP10 Products)

Synonyms: BMP10 antibody, si:dkey-13n15.5 antibody, Bmp10 antibody, BMP9 antibody, BMP-10 antibody, bone morphogenetic protein 10 antibody, BMP10 antibody, bmp10 antibody, LOC662386 antibody, Bmp10 antibody

Background: Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth. Synonyms: Polyclonal Bmp10 antibody, Anti-Bmp10 antibody, bone morphogenetic protein 10 antibody, Bmp10 antibody.

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation