RAG1 antibody (C-Term)

Catalog No. ABIN928010

Product Details anti-RAG1 Antibody

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Binding Specificity: C-Term

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAG1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine)

Purification: Purified

Immunogen: Rag1 antibody was raised in rabbit using the C terminal of Rag1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Rag1 Blocking Peptide, catalog no. 33R-3994, is also available for use as a blocking control in assays to test for specificity of this Rag1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RAG1

Target: RAG1 (Recombination Activating Gene 1 (RAG1))

Alternative Name: Rag1 (RAG1 Products)

Synonyms: RAG-1 antibody, rag1 antibody, RNF74 antibody, Rag-1 antibody, rag-1 antibody, rag1a antibody, recombination activating 1 antibody, recombination activating gene 1 antibody, recombination activating gene 1 S homeolog antibody, Rag1 antibody, RAG1 antibody, rag1 antibody, rag1.S antibody

Background: As a catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. Synonyms: Polyclonal Rag1 antibody, Anti-Rag1 antibody, recombination activating gene 1 antibody, Rag-1 antibody.