RNF34 antibody (Middle Region)

Catalog No. ABIN927926

Product Details anti-RNF34 Antibody

Target: RNF34 (Ring Finger Protein 34 (RNF34))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF34 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Cow (Bovine), Chicken

Purification: Purified

Immunogen: RNF34 antibody was raised in rabbit using the middle region of RNF34 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RNF34 Blocking Peptide, catalog no. 33R-5504, is also available for use as a blocking control in assays to test for specificity of this RNF34 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RNF34

Target: RNF34 (Ring Finger Protein 34 (RNF34))

Alternative Name: RNF34 (RNF34 Products)

Synonyms: CARP-1 antibody, CARP1 antibody, RFI antibody, RIF antibody, RIFF antibody, hRFI antibody, rnf34 antibody, AW061037 antibody, AW536122 antibody, BC004042 antibody, C88279 antibody, Momo antibody, fi35g06 antibody, wu:fi35g06 antibody, zgc:114043 antibody, zgc:171755 antibody, ring finger protein 34 antibody, E3 ubiquitin-protein ligase RNF34 antibody, ring finger protein 34a antibody, ring finger protein 34b antibody, Residual feed intake antibody, RNF34 antibody, rnf34 antibody, Rnf34 antibody, rnf34a antibody, rnf34b antibody, RFI antibody

Background: RNF34 contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. Synonyms: Polyclonal RNF34 antibody, Anti-RNF34 antibody, ring finger protein 34 antibody, FLJ21786 antibody, RFI antibody, RIF antibody, RIFF antibody.