KLHL12 antibody (N-Term)

Catalog No. ABIN927821

Product Details anti-KLHL12 Antibody

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Binding Specificity: N-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL12 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus)

Purification: Purified

Immunogen: Klhl12 antibody was raised in rabbit using the N terminal of Klhl12 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

Klhl12 Blocking Peptide, catalog no. 33R-2002, is also available for use as a blocking control in assays to test for specificity of this Klhl12 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for KLHL12

Target: KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))

Alternative Name: Klhl12 (KLHL12 Products)

Synonyms: zgc:92570 antibody, wu:fi60g03 antibody, C3ip1 antibody, C3IP1 antibody, DKIR antibody, hDKIR antibody, Ski2 like RNA helicase antibody, kelch like family member 12 L homeolog antibody, kelch like family member 12 antibody, kelch-like family member 12 antibody, kelch-like 12 antibody, SKIV2L antibody, klhl12.L antibody, KLHL12 antibody, klhl12 antibody, Klhl12 antibody

Background: Klhl12 serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. It negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3. Synonyms: Polyclonal Klhl12 antibody, Anti-Klhl12 antibody, kelch-like 12, Drosophila antibody, C3ip1 antibody, MGC93127 antibody.