HBP1 antibody (Middle Region)

Catalog No. ABIN927751

Product Details anti-HBP1 Antibody

Target: HBP1 (HMG Box-Containing Protein 1 (HBP1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Chicken, Zebrafish (Danio rerio), Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Cow (Bovine), Frog, Dog (Canine), Chicken, Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: HBP1 antibody was raised in rabbit using the middle region of HBP1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HBP1 Blocking Peptide, catalog no. 33R-8913, is also available for use as a blocking control in assays to test for specificity of this HBP1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for HBP1

Target: HBP1 (HMG Box-Containing Protein 1 (HBP1))

Alternative Name: HBP1 (HBP1 Products)

Synonyms: 1700058O05Rik antibody, BE629963 antibody, C330012F01Rik antibody, C86454 antibody, hbp1-B antibody, Hmgb1 antibody, wu:fj62c10 antibody, zgc:112297 antibody, high mobility group box transcription factor 1 antibody, HMG-box transcription factor 1 antibody, HMG-box transcription factor 1 L homeolog antibody, Hbp1 antibody, HBP1 antibody, hbp1.L antibody, hbp1 antibody

Background: HBP1 is a transcriptional repressor that binds to the promoter region of target genes. This protein plays a role in the regulation of the cell cycle and of the Wnt pathway. It binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter, HBP1 is enhanced by interaction with RB1. The protein also can disrupt the interaction between DNA and TCF4. Synonyms: Polyclonal HBP1 antibody, Anti-HBP1 antibody, HMG-box transcription factor 1 antibody, FLJ16340 antibody.