SOX4 antibody (N-Term)

Catalog No. ABIN927705

Product Details anti-SOX4 Antibody

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX4 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Chicken, Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: SOX4 antibody was raised in rabbit using the N terminal of SOX4 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

SOX4 Blocking Peptide, catalog no. 33R-8865, is also available for use as a blocking control in assays to test for specificity of this SOX4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SOX4

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Alternative Name: SOX4 (SOX4 Products)

Synonyms: EVI16 antibody, AA682046 antibody, Sox-4 antibody, sox4 antibody, wu:fb82f08 antibody, wu:fq41g10 antibody, zgc:65850 antibody, zgc:77392 antibody, SRY-box 4 antibody, SRY box 4 antibody, SRY (sex determining region Y)-box 4 antibody, SRY (sex determining region Y)-box 4a antibody, SOX4 antibody, Sox4 antibody, sox4a antibody

Background: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. Synonyms: Polyclonal SOX4 antibody, Anti-SOX4 antibody, SRY, sex determining region Y-box 4 antibody, EVI16 antibody.