SSX2 antibody (C-Term)

Catalog No. ABIN927674

Product Details anti-SSX2 Antibody

Target: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSX2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: SSX2 antibody was raised in rabbit using the C terminal of SSX2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

SSX2 Blocking Peptide, catalog no. 33R-3849, is also available for use as a blocking control in assays to test for specificity of this SSX2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SSX2

Target: SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Alternative Name: SSX2 (SSX2 Products)

Synonyms: CT5.2 antibody, CT5.2A antibody, HD21 antibody, HOM-MEL-40 antibody, SSX antibody, SSX2 antibody, SSX3 antibody, SSX family member 2 antibody, protein SSX2 antibody, synovial sarcoma, X breakpoint 2 antibody, SSX2 antibody, LOC741661 antibody, Ssx2 antibody

Background: SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. Synonyms: Polyclonal SSX2 antibody, Anti-SSX2 antibody, synovial sarcoma, X breakpoint 2 antibody, HD21 antibody, HOM-MEL-40 antibody, MGC119055 antibody, MGC15364 antibody, MGC3884 antibody, SSX antibody.