Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ACD antibody (C-Term)

ACD Reactivity: Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN927647
  • Target See all ACD Antibodies
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Binding Specificity
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 32
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    Mouse
    Host
    • 26
    • 7
    • 1
    Rabbit
    Clonality
    • 29
    • 5
    Polyclonal
    Conjugate
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACD antibody is un-conjugated
    Application
    • 23
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Purified
    Immunogen
    Acd antibody was raised in rabbit using the c terminal of Acd as the immunogen
    Top Product
    Discover our top product ACD Primary Antibody
  • Application Notes
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    Acd Blocking Peptide, catalog no. 33R-7345, is also available for use as a blocking control in assays to test for specificity of this Acd antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Target
    ACD (Adrenocortical Dysplasia Homolog (ACD))
    Alternative Name
    Acd (ACD Products)
    Synonyms
    PIP1 antibody, PTOP antibody, TINT1 antibody, TPP1 antibody, ACD antibody, ACD, shelterin complex subunit and telomerase recruitment factor antibody, adrenocortical dysplasia antibody, ACD antibody, Acd antibody
    Background
    Acd is a component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.Acd promotes binding of POT1 to single-stranded telomeric DNA.Acd modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomer elongation by increasing telomerase processivity.Acd plays a role in shelterin complex assembly. Acd may play an essential role in organogenesis of the developing embryo. Synonyms: Polyclonal Acd antibody, Anti-Acd antibody, adrenocortical dysplasia antibody.
    Pathways
    Telomere Maintenance
You are here:
Support