Metabotropic Glutamate Receptor 6 antibody (C-Term)

Catalog No. ABIN927397

Product Details anti-Metabotropic Glutamate Receptor 6 Antibody

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Metabotropic Glutamate Receptor 6 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Rabbit, Chicken

Purification: Purified

Immunogen: GRM6 antibody was raised in rabbit using the C terminal of GRM6 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

GRM6 Blocking Peptide, catalog no. 33R-4175, is also available for use as a blocking control in assays to test for specificity of this GRM6 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Metabotropic Glutamate Receptor 6

Target: Metabotropic Glutamate Receptor 6 (GRM6) (Glutamate Receptor, Metabotropic 6 (GRM6))

Alternative Name: GRM6 (GRM6 Products)

Background: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. GRM6 is part of Group III which is linked to the inhibition of the cyclic AMP cascade. Synonyms: Polyclonal GRM6 antibody, Anti-GRM6 antibody, glutamate receptor, metabotropic 6 antibody.