STXBP1 antibody (Middle Region)

Catalog No. ABIN926990

Product Details anti-STXBP1 Antibody

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Chicken, Xenopus laevis, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Chicken, Frog, Cow (Bovine), Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: STXBP1 antibody was raised in rabbit using the middle region of STXBP1 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

STXBP1 Blocking Peptide, catalog no. 33R-9269, is also available for use as a blocking control in assays to test for specificity of this STXBP1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for STXBP1

Target: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Alternative Name: STXBP1 (STXBP1 Products)

Background: STXBP1 belongs to the STXBP/unc-18/SEC1 family. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4. Synonyms: Polyclonal STXBP1 antibody, Anti-STXBP1 antibody, syntaxin binding protein 1 antibody, MUNC18-1 antibody, UNC18 antibody, hUNC18 antibody, rbSec1 antibody.

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport