RAB8A antibody (Middle Region)

Catalog No. ABIN926981

Product Details anti-RAB8A Antibody

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB8A antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Dog (Canine), Mouse (Murine), Rat (Rattus), Frog, Chicken, Cow (Bovine), Zebrafish (Brachydanio rerio)

Purification: Purified

Immunogen: RAB8 A antibody was raised in rabbit using the middle region of RAB8 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RAB8A Blocking Peptide, catalog no. 33R-3327, is also available for use as a blocking control in assays to test for specificity of this RAB8A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RAB8A

Target: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Alternative Name: RAB8A (RAB8A Products)

Synonyms: rab8A antibody, DDBDRAFT_0206521 antibody, DDBDRAFT_0214885 antibody, DDB_0206521 antibody, DDB_0214885 antibody, HSH2D antibody, mel antibody, rab8 antibody, c-mel antibody, MEL antibody, RAB8 antibody, zgc:162699 antibody, AA409338 antibody, Mel antibody, Rab8 antibody, rab8A protein antibody, Rab GTPase antibody, RAB8A, member RAS oncogene family antibody, RAB8A, member RAS oncogene family S homeolog antibody, rab8A antibody, RAB8A antibody, rab8a antibody, rab8a.S antibody, Rab8a antibody

Background: RAB8A is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. Synonyms: Polyclonal RAB8A antibody, Anti-RAB8A antibody, RAB8A, member RAS oncogene family antibody, MEL antibody, RAB8 antibody.

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome