Serotonin Receptor 4 antibody (Middle Region)

Catalog No. ABIN926963

Product Details anti-Serotonin Receptor 4 Antibody

Target: Serotonin Receptor 4 (HTR4)

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 4 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus), Mouse (Murine), Dog (Canine), Pig (Porcine), Cow (Bovine)

Purification: Purified

Immunogen: HTR4 antibody was raised in rabbit using the middle region of HTR4 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

HTR4 Blocking Peptide, catalog no. 33R-3194, is also available for use as a blocking control in assays to test for specificity of this HTR4 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Serotonin Receptor 4

Target: Serotonin Receptor 4 (HTR4)

Alternative Name: HTR4 (HTR4 Products)

Synonyms: 5-HT4 antibody, 5-HT<4L> antibody, 5HTR4 antibody, 5-HT4S antibody, 5-HT4R antibody, 5 hydroxytryptamine (serotonin) receptor 4 antibody, 5-hydroxytryptamine receptor 4 antibody, Htr4 antibody, HTR4 antibody

Background: HTR4 is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The protein is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined. Synonyms: Polyclonal HTR4 antibody, Anti-HTR4 antibody, 5-hydroxytryptamine, serotonin receptor 4 antibody, 5-HT4 antibody, 5-HT4R antibody.

Pathways: JAK-STAT Signaling, cAMP Metabolic Process, S100 Proteins