Caveolin 3 antibody (N-Term)

Catalog No. ABIN926940

Product Details anti-Caveolin 3 Antibody

Target: Caveolin 3 (CAV3)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Dog (Canine), Mouse (Murine), Rat (Rattus), Cow (Bovine), Pig (Porcine)

Purification: Purified

Immunogen: CAV3 antibody was raised in rabbit using the N terminal of CAV3 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

CAV3 Blocking Peptide, catalog no. 33R-6224, is also available for use as a blocking control in assays to test for specificity of this CAV3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Caveolin 3

Target: Caveolin 3 (CAV3)

Alternative Name: CAV3 (CAV3 Products)

Synonyms: LGMD1C antibody, LQT9 antibody, VIP-21 antibody, VIP21 antibody, AI385751 antibody, Cav-3 antibody, M-cav antibody, caveolin-3 antibody, im:6902906 antibody, zgc:109710 antibody, LOC733765 antibody, CAV3 antibody, cav3 antibody, caveolin 3 antibody, caveolin-3 antibody, CAV3 antibody, Cav3 antibody, cav3 antibody, LOC733765 antibody, cav-3 antibody

Background: CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Synonyms: Polyclonal CAV3 antibody, Anti-CAV3 antibody, caveolin 3 antibody.

Pathways: Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity