Insulin Receptor antibody (Middle Region)
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- Target See all Insulin Receptor (INSR) Antibodies
- Insulin Receptor (INSR)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Zebrafish (Danio rerio), Xenopus laevis
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Insulin Receptor antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus), Dog (Canine), Rabbit, Zebrafish (Brachydanio rerio), Frog
- Purification
- Purified
- Immunogen
- INSR antibody was raised in rabbit using the middle region of INSR as the immunogen
- Top Product
- Discover our top product INSR Primary Antibody
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anti-Insulin Receptor (INSR) antibody
INSR Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C19 unconjugated
anti-Insulin Receptor (INSR) (AA 1024-1298) antibodyINSR Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1027-1364) antibodyINSR Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1101-1372) antibodyINSR Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibodyINSR Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB1421 unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyINSR Reactivity: Human, Mouse, Rat, Dog, Monkey, Horse, Cow, Guinea Pig, Pig, Rabbit, Chicken, Sheep, Hamster, Goat, Avian, Cat, Donkey WB Host: Goat Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyKO Validated INSR Reactivity: Human WB, ICC, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1325-1358) antibodyINSR Reactivity: Mouse WB Host: Rabbit Polyclonal RB50340 unconjugated
anti-Insulin Receptor (INSR) (AA 1023-1298) antibodyINSR Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 51-150) antibodyINSR Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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INSR Blocking Peptide, catalog no. 33R-8809, is also available for use as a blocking control in assays to test for specificity of this INSR antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- Insulin Receptor (INSR)
- Alternative Name
- INSR (INSR Products)
- Background
- This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). INSR can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When present in a hybrid receptor with IGF1R, it binds IGF1. Synonyms: Polyclonal INSR antibody, Anti-INSR antibody, insulin receptor antibody, CD220 antibody, HHF5 antibody.
- Pathways
- NF-kappaB Signaling, RTK Signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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