BIRC7 antibody (Middle Region)
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- Target See all BIRC7 Antibodies
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
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Binding Specificity
- Middle Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BIRC7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Purified
- Immunogen
- BIRC7 antibody was raised in rabbit using the middle region of BIRC7 as the immunogen
- Top Product
- Discover our top product BIRC7 Primary Antibody
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- Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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BIRC7 Blocking Peptide, catalog no. 33R-2387, is also available for use as a blocking control in assays to test for specificity of this BIRC7 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))
- Alternative Name
- BIRC7 (BIRC7 Products)
- Synonyms
- KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody, EIAP/XLX antibody, XLX antibody, kiap antibody, livin antibody, ml-iap antibody, mliap antibody, rnf50 antibody, xEIAP antibody, RGD1562883 antibody, zgc:165605 antibody, E130019N06 antibody, Livin antibody, birc7 antibody, bird7a antibody, xEIAP/XLX antibody, xlx antibody, EIAP/XLX-B antibody, birc7b antibody, baculoviral IAP repeat containing 7 antibody, baculoviral IAP repeat-containing 7 antibody, baculoviral IAP repeat-containing 7 (livin) antibody, baculoviral IAP repeat containing 7 S homeolog antibody, baculoviral IAP repeat containing 7 L homeolog antibody, BIRC7 antibody, birc7 antibody, Birc7 antibody, birc7.S antibody, birc7.L antibody
- Background
- BIRC7 protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Synonyms: Polyclonal BIRC7 antibody, Anti-BIRC7 antibody, baculoviral IAP repeat-containing 7, livin antibody, KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody.
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