VNN2 antibody (C-Term)

Catalog No. ABIN926799

Product Details anti-VNN2 Antibody

Target: VNN2 (Vanin 2 (VNN2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VNN2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: VNN2 antibody was raised in rabbit using the C terminal of VNN2 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

VNN2 Blocking Peptide, catalog no. 33R-3046, is also available for use as a blocking control in assays to test for specificity of this VNN2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for VNN2

Target: VNN2 (Vanin 2 (VNN2))

Alternative Name: VNN2 (VNN2 Products)

Synonyms: FOAP-4 antibody, GPI-80 antibody, vanin 2 antibody, vascular non-inflammatory molecule 2 antibody, VNN2 antibody, LOC100067672 antibody, LOC100345689 antibody, LOC100436777 antibody

Background: This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Synonyms: Polyclonal VNN2 antibody, Anti-VNN2 antibody, vanin 2 antibody, FOAP-4 antibody, GPI-80 antibody.