SURF1 antibody (N-Term)

Catalog No. ABIN926757

Product Details anti-SURF1 Antibody

Target: SURF1 (Surfeit 1 (SURF1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SURF1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: SURF1 antibody was raised in rabbit using the N terminal of SURF1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

SURF1 Blocking Peptide, catalog no. 33R-3415, is also available for use as a blocking control in assays to test for specificity of this SURF1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for SURF1

Target: SURF1 (Surfeit 1 (SURF1))

Alternative Name: SURF1 (SURF1 Products)

Synonyms: BcDNA:GH23574 antibody, CG9943 antibody, Dmel\\CG9943 antibody, GB14201 antibody, SURF1 antibody, im:6898613 antibody, zgc:158646 antibody, Ab1-205 antibody, SURF-1 antibody, 0610010F23Rik antibody, Surf-1 antibody, SURFEIT 1 antibody, Surfeit 1 antibody, surfeit locus protein 1 antibody, SURF1, cytochrome c oxidase assembly factor antibody, surfeit 1 antibody, surfeit gene 1 antibody, Surfeit locus 1 cytochrome c oxidase biogenesis protein antibody, Surf1 antibody, LOC413781 antibody, SURF1 antibody, surf1 antibody

Background: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. Synonyms: Polyclonal SURF1 antibody, Anti-SURF1 antibody, surfeit 1 antibody.

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process