RCC1 antibody (C-Term)

Catalog No. ABIN926713

Product Details anti-RCC1 Antibody

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCC1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: RCC1 antibody was raised in rabbit using the C terminal of RCC1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

RCC1 Blocking Peptide, catalog no. 33R-1623, is also available for use as a blocking control in assays to test for specificity of this RCC1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Alternative Name: RCC1 (RCC1 Products)

Synonyms: Chc1 antibody, zgc:65796 antibody, zgc:77114 antibody, wu:fj77f08 antibody, rcc1 antibody, chc1-a antibody, BJ1 antibody, CG10480 antibody, CG18640 (Bj1) antibody, Dmel\\CG10480 antibody, RCC1 antibody, RanGEF antibody, Rcc1 antibody, dRCC1 antibody, inxs antibody, sdt antibody, xrcc1 antibody, chc1-b antibody, MGC115703 antibody, MGC132085 antibody, CHC1 antibody, RCC1-I antibody, SNHG3-RCC1 antibody, 4931417M11Rik antibody, AI326872 antibody, regulator of chromosome condensation 1 antibody, regulator of chromosome condensation 1 L homeolog antibody, Regulator of chromosome condensation 1 antibody, N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted antibody, regulator of chromosome condensation 1 S homeolog antibody, rcc1 antibody, RCC1 antibody, rcc1.L antibody, Rcc1 antibody, rcc1.S antibody

Background: RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly. Synonyms: Polyclonal RCC1 antibody, Anti-RCC1 antibody, regulator of chromosome condensation 1 antibody, CHC1 antibody, RCC1-I antibody.

Pathways: Chromatin Binding, Protein targeting to Nucleus