Desmoglein 3 antibody (C-Term)

Catalog No. ABIN926701

Product Details anti-Desmoglein 3 Antibody

Target: Desmoglein 3 (DSG3)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoglein 3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: DSG3 antibody was raised in rabbit using the C terminal of DSG3 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

DSG3 Blocking Peptide, catalog no. 33R-4480, is also available for use as a blocking control in assays to test for specificity of this DSG3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Desmoglein 3

Target: Desmoglein 3 (DSG3)

Alternative Name: DSG3 (DSG3 Products)

Synonyms: DSG3 antibody, CDHF6 antibody, PVA antibody, bal antibody, balding antibody, desmoglein 3 antibody, DSG3 antibody, Dsg3 antibody

Background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. Synonyms: Polyclonal DSG3 antibody, Anti-DSG3 antibody, desmoglein 3 antibody, CDHF6 antibody, DKFZp686P23184 antibody, PVA antibody.