IDS antibody (N-Term)

Catalog No. ABIN926632

Product Details anti-IDS Antibody

Target: IDS (Iduronate 2-Sulfatase (IDS))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDS antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: IDS antibody was raised in rabbit using the N terminal of IDS as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

IDS Blocking Peptide, catalog no. 33R-8437, is also available for use as a blocking control in assays to test for specificity of this IDS antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for IDS

Target: IDS (Iduronate 2-Sulfatase (IDS))

Alternative Name: IDS (IDS Products)

Synonyms: mps2 antibody, sids antibody, zgc:158245 antibody, MPS2 antibody, SIDS antibody, AW214631 antibody, iduronate 2-sulfatase antibody, IDS antibody, CpipJ_CPIJ004938 antibody, ids antibody, Ids antibody

Background: Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. Synonyms: Polyclonal IDS antibody, Anti-IDS antibody, iduronate 2-sulfatase antibody, MPS2 antibody, SIDS antibody.

Pathways: Glycosaminoglycan Metabolic Process