Kdm6b antibody (Middle Region)

Catalog No. ABIN925949

Product Details anti-Kdm6b Antibody

Target: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kdm6b antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus), Dog (Canine), Frog

Immunogen: JMJD3 antibody was raised in rabbit using the middle region of JMJD3 as the immunogen

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

JMJD3 Blocking Peptide, catalog no. 33R-1207, is also available for use as a blocking control in assays to test for specificity of this JMJD3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Kdm6b

Target: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Alternative Name: JMJD3 (Kdm6b Products)

Synonyms: jmjd3 antibody, kdm6b antibody, si:ch211-237l4.7 antibody, 1700064E03Rik antibody, BC038313 antibody, Jmjd3 antibody, mKIAA0346 antibody, JMJD3 antibody, lysine (K)-specific demethylase 6B antibody, lysine demethylase 6B antibody, lysine (K)-specific demethylase 6B, b antibody, KDM1 lysine (K)-specific demethylase 6B antibody, kdm6b antibody, KDM6B antibody, kdm6bb antibody, Kdm6b antibody

Background: JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. Synonyms: Polyclonal JMJD3 antibody, Anti-JMJD3 antibody, jumonji domain containing 3, histone lysine demethylase antibody, KIAA0346 antibody.

Pathways: Warburg Effect