RFX5 antibody (N-Term)

Catalog No. ABIN925889

Product Details anti-RFX5 Antibody

Target: RFX5 (Regulatory Factor X 5 (RFX5))

Binding Specificity: N-Term

Reactivity: Human, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFX5 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rabbit, Dog (Canine)

Immunogen: RFX5 antibody was raised in rabbit using the N terminal of RFX5 as the immunogen

Application Details

Application Notes: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RFX5 Blocking Peptide, catalog no. 33R-5632, is also available for use as a blocking control in assays to test for specificity of this RFX5 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for RFX5

Target: RFX5 (Regulatory Factor X 5 (RFX5))

Alternative Name: RFX5 (RFX5 Products)

Synonyms: regulatory factor X5 antibody, regulatory factor X, 5 (influences HLA class II expression) antibody, RFX5 antibody, Rfx5 antibody

Background: RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. RFX is a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX.A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome. Synonyms: Polyclonal RFX5 antibody, Anti-RFX5 antibody, regulatory factor X, 5, influences HLA class II expression antibody.