Mesp2 antibody (C-Term)

Catalog No. ABIN925827

Product Details anti-Mesp2 Antibody

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Binding Specificity: C-Term

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mesp2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat (Rattus)

Immunogen: MESP2 antibody was raised in rabbit using the C terminal of MESP2 as the immunogen

Application Details

Application Notes: WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

MESP2 Blocking Peptide, catalog no. 33R-8337, is also available for use as a blocking control in assays to test for specificity of this MESP2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Mesp2

Target: Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))

Alternative Name: MESP2 (Mesp2 Products)

Synonyms: bHLHc6 antibody, SCDO2 antibody, mesoderm posterior 2 antibody, mesoderm posterior bHLH transcription factor 2 antibody, Mesp2 antibody, MESP2 antibody

Background: Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2. Synonyms: Polyclonal MESP2 antibody, Anti-MESP2 antibody.