ACTC1 antibody

Catalog No. ABIN920523

Product Details anti-ACTC1 Antibody

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Reactivity: Human, Rat, Zebrafish (Danio rerio), Rabbit, Pig, Goat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACTC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: The epitope recognized by alpha-SM1 is highly conserved. The antibody therefore cross-reacts with many species including protochordates, lower craniates and mammals.

Characteristics: Cytoskeletal

Clone: 22D3

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

References for anti-ACTC1 antibody (ABIN920523)

Driesen, Verheyen, Debie, Blaauw, Babiker, Cornelussen, Ausma, Lenders, Borgers, Chaponnier, Ramaekers: "Re-expression of alpha skeletal actin as a marker for dedifferentiation in cardiac pathologies." in: Journal of cellular and molecular medicine, Vol. 13, Issue 5, pp. 896-908, (2009) (PubMed).

Chaponnier, Gabbiani: "Pathological situations characterized by altered actin isoform expression." in: The Journal of pathology, Vol. 204, Issue 4, pp. 386-95, (2004) (PubMed).

Suurmeijer, Clément, Francesconi, Bocchi, Angelini, Van Veldhuisen, Spagnoli, Gabbiani, Orlandi: "Alpha-actin isoform distribution in normal and failing human heart: a morphological, morphometric, and biochemical study." in: The Journal of pathology, Vol. 199, Issue 3, pp. 387-97, (2003) (PubMed).

Vandekerckhove, Bugaisky, Buckingham: "Simultaneous expression of skeletal muscle and heart actin proteins in various striated muscle tissues and cells. A quantitative determination of the two actin isoforms." in: The Journal of biological chemistry, Vol. 261, Issue 4, pp. 1838-43, (1986) (PubMed).

Vandekerckhove, Weber: "At least six different actins are expressed in a higher mammal: an analysis based on the amino acid sequence of the amino-terminal tryptic peptide." in: Journal of molecular biology, Vol. 126, Issue 4, pp. 783-802, (1979) (PubMed).

Target Details for ACTC1

Target: ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))

Alternative Name: Actin alpha-Cardiac (ACTC1 Products)

Pathways: Myometrial Relaxation and Contraction