Actin antibody

Catalog No. ABIN920521

This Mouse Monoclonal antibody specifically detects Actin in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Rat, Rabbit, Pig and Goat and has been mentioned in 5+ publications.

Quick Overview for Actin antibody (ABIN920521)

Target: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Reactivity: Human, Rat, Rabbit, Pig, Goat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Actin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 3B3

Product Details anti-Actin Antibody

Specificity: The epitope recognized by alpha-SM1 is highly conserved. The antibody therefore cross-reacts with many species including protochordates, lower craniates and mammals.

Characteristics: Cytoskeletal

Isotype: IgG1

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

References for anti-Actin antibody (ABIN920521)

Driesen, Verheyen, Debie, Blaauw, Babiker, Cornelussen, Ausma, Lenders, Borgers, Chaponnier, Ramaekers: "Re-expression of alpha skeletal actin as a marker for dedifferentiation in cardiac pathologies." in: Journal of cellular and molecular medicine, Vol. 13, Issue 5, pp. 896-908, (2009) (PubMed).

Chaponnier, Gabbiani: "Pathological situations characterized by altered actin isoform expression." in: The Journal of pathology, Vol. 204, Issue 4, pp. 386-95, (2004) (PubMed).

Suurmeijer, Clément, Francesconi, Bocchi, Angelini, Van Veldhuisen, Spagnoli, Gabbiani, Orlandi: "Alpha-actin isoform distribution in normal and failing human heart: a morphological, morphometric, and biochemical study." in: The Journal of pathology, Vol. 199, Issue 3, pp. 387-97, (2003) (PubMed).

Vandekerckhove, Bugaisky, Buckingham: "Simultaneous expression of skeletal muscle and heart actin proteins in various striated muscle tissues and cells. A quantitative determination of the two actin isoforms." in: The Journal of biological chemistry, Vol. 261, Issue 4, pp. 1838-43, (1986) (PubMed).

Vandekerckhove, Weber: "At least six different actins are expressed in a higher mammal: an analysis based on the amino acid sequence of the amino-terminal tryptic peptide." in: Journal of molecular biology, Vol. 126, Issue 4, pp. 783-802, (1979) (PubMed).

Target Details for Actin

Target: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Alternative Name: Actin alpha-Skeletal

Pathways: Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development