TNIP3 antibody (AA 51-150) (Biotin)

Catalog No. ABIN918071

Product Details anti-TNIP3 Antibody (Biotin)

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Binding Specificity: AA 51-150

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIP3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNFAIP3 interacting protein 3/ABIN3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TNIP3

Target: TNIP3 (TNFAIP3 Interacting Protein 3 (TNIP3))

Alternative Name: TNFAIP3 interacting protein 3 (TNIP3 Products)

Synonyms: ABIN-3 antibody, LIND antibody, 9030611K07Rik antibody, TNIP3 antibody, TNFAIP3 interacting protein 3 antibody, TNIP3 antibody, Tnip3 antibody

Background:

Synonyms: Listeria induced, A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3, ABIN-3 beta, FLJ21162, LIND, Listeria induced gene protein, TNFAIP3 interacting protein 3, TNFAIP3-interacting protein 3 beta, TNIP3, TNIP3 beta, TNIP3_HUMAN.

Background: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.

Gene ID: 7128

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin