SMC6 antibody (AA 155-260) (HRP)

Catalog No. ABIN915847

Product Details anti-SMC6 Antibody (HRP)

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Binding Specificity: AA 155-260

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC6 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SMC6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SMC6

Target: SMC6 (SMC6 Structural Maintenance of Chromosomes 6-Like 1 (SMC6))

Alternative Name: SMC6 (SMC6 Products)

Synonyms: SMC6L1 antibody, SMC-6 antibody, hSMC6 antibody, 2810489L22Rik antibody, 3830418C19Rik antibody, AA990493 antibody, AU018782 antibody, AW742439 antibody, Smc6l1 antibody, mKIAA4103 antibody, structural maintenance of chromosomes 6 antibody, SMC6 antibody, smc6 antibody, Smc6 antibody

Background:

Synonyms: SMC6L1, SMC 6, SMC6, SMC6 protein, SMC6 structural maintenance of chromosomes 6 like 1, Structural maintenance of chromosomes 6, Structural maintenance of chromosomes 6 like 1, Structural maintenance of chromosomes protein 6.

Background: SMC5/6 complex is recruited to nuclease induced double strand breaks (DSBs) and is required for the recruitment of cohesin to DSBs. The human SMC5/6 complex and the SUMO ligase activity of hMMS21 are required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells.

Gene ID: 79677