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PLSCR3 antibody (AA 201-295) (AbBy Fluor® 350)

PLSCR3 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN911538
  • Target See all PLSCR3 Antibodies
    PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
    Binding Specificity
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-295
    Reactivity
    • 26
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 23
    • 5
    Rabbit
    Clonality
    • 23
    • 5
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLSCR3 antibody is conjugated to AbBy Fluor® 350
    Application
    • 13
    • 12
    • 12
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PLSCR3
    Isotype
    IgG
    Top Product
    Discover our top product PLSCR3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
    Alternative Name
    PLSCR3 (PLSCR3 Products)
    Synonyms
    2210403O21Rik antibody, 2610037N06Rik antibody, ESTM3 antibody, X83310 antibody, Pls3 antibody, zgc:77051 antibody, phospholipid scramblase 3 antibody, phospholipid scramblase 3b antibody, PLSCR3 antibody, Plscr3 antibody, plscr3b antibody
    Background

    Synonyms: Ca2+-dependent phospholipid scramblase 3, Phospholipid scramblase 3, PL scramblase 3, PLS3, PLS3_HUMAN.

    Background: PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

    Gene ID
    57048
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
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