PLCL1 antibody (AA 1001-1096) (AbBy Fluor® 488)

Catalog No. ABIN911381

Product Details anti-PLCL1 Antibody (AbBy Fluor® 488)

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Binding Specificity: AA 1001-1096

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCL1 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Specificity: This antibody may exhibit a slight secondary cross-reactivity with PLCL2 due to a 69 % non-sequential sequence similarity over the immunogen range.

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLCL1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PLCL1

Target: PLCL1 (phospholipase C-Like 1 (PLCL1))

Alternative Name: PLCL1 (PLCL1 Products)

Synonyms: PLCE antibody, PLCL antibody, PLDL1 antibody, PRIP antibody, C230017K02Rik antibody, PLC-L antibody, PLC-L1 antibody, PRIP-1 antibody, phospholipase C like 1 (inactive) antibody, phospholipase C-like 1 antibody, PLCL1 antibody, Plcl1 antibody

Background:

Synonyms: PLCL1, PLCE, Phospholipase C deleted in lung carcinoma, Phospholipase C epsilon, Phospholipase C like 1, Phospholipase C related but catalytically inactive protein, Phospholipase C related, but catalytically inactive protein, PLCE, PLCL, PRIP, Plcl1, C230017K02Rik, KIAA1092, PLC-L, PLC-L1, PLCE, PLCL, PRIP, PRIP-1, PLCL1_HUMAN.

Background: PLCL1 is involved an inositol phospholipid based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and sphatidylinositol. Component in the dependent endocytosis process of GABA A receptor (By similarity). Regulates the turnover of receptors and thus contributes to the maintenance of GABA mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.

Gene ID: 5334