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PLCz1 antibody (AA 351-450) (AbBy Fluor® 555)

PLCz1 Reactivity: Rat IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 555
Catalog No. ABIN911375
  • Target See all PLCz1 Antibodies
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Binding Specificity
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivity
    • 20
    • 14
    • 4
    Rat
    Host
    • 33
    • 2
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLCz1 antibody is conjugated to AbBy Fluor® 555
    Application
    • 12
    • 12
    • 12
    • 10
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PLCZ1
    Isotype
    IgG
    Top Product
    Discover our top product PLCz1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PLCz1 (Phospholipase C zeta 1 (PLCz1))
    Alternative Name
    PLCZ1 (PLCz1 Products)
    Synonyms
    PLC-zeta-1 antibody, PLCZ1 antibody, 1700041H07Rik antibody, PLCzeta antibody, NYD-SP27 antibody, PLCZ antibody, phospholipase C zeta 1 antibody, phospholipase C, zeta 1 antibody, PLCZ1 antibody, Plcz1 antibody
    Background

    Synonyms: PLCzeta, NYD-SP27, PLC-zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1, Phosphoinositide phospholipase C-zeta-1, Phospholipase C-zeta-1, Testis-development protein NYD-SP27, PLCZ1, PLCZ1_HUMAN

    Background: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

    Gene ID
    89869
    UniProt
    Q86YW0
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