SPDEF/PSE antibody (AA 251-335) (AbBy Fluor® 555)
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- Target See all SPDEF/PSE (SPDEF) Antibodies
- SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
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Binding Specificity
- AA 251-335
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPDEF/PSE antibody is conjugated to AbBy Fluor® 555
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Application
- Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PDEF
- Isotype
- IgG
- Top Product
- Discover our top product SPDEF Primary Antibody
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- Application Notes
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))
- Alternative Name
- Pdef/Spdef (SPDEF Products)
- Synonyms
- PDEF antibody, RP11-375E1__A.3 antibody, bA375E1.3 antibody, pdef antibody, Pse antibody, SAM pointed domain containing ETS transcription factor antibody, SAM pointed domain containing ets transcription factor antibody, SPDEF antibody, Spdef antibody
- Background
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Synonyms: bA375E1.3, PDEF, Prostate derived Ets factor, PROSTATE EPITHELIUM SPECIC ETS TRANSCRIPTION FACTOR, Prostate epithelium-specic Ets transcription factor, Prostate specic Ets, Prostate-derived Ets factor, Prostate-specic Ets, PSE, RP11-375E1__A.3, SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR, SAM pointed domain-containing Ets transcription factor, Spdef, SPDEF_HUMAN.
Background: SPDEF, also known as PDEF is an ETS transcription factor expressed in the prostate epithelial cells. It is thought to act as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter and also as a transcriptional activator for the SERPINB5 promoter. It is highly expressed in prostate carcinoma cells and is thought to be involved in the regulation of the prostate gland and/or prostate cancer development. It is also expressed in epithelial breast carcinoma.
- Gene ID
- 25803
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