DPH1 antibody (AA 251-350) (AbBy Fluor® 488)

Catalog No. ABIN909599

Product Details anti-DPH1 Antibody (AbBy Fluor® 488)

Target: DPH1 (DPH1 Homolog (DPH1))

Binding Specificity: AA 251-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPH1 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OVCA1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DPH1

Target: DPH1 (DPH1 Homolog (DPH1))

Alternative Name: OVCA1 (DPH1 Products)

Synonyms: DPH1 antibody, DPH1-OVCA2 antibody, dph1-ovca2 antibody, dph2l antibody, dph2l1 antibody, ovca1 antibody, DPH2L antibody, DPH2L1 antibody, OVCA1 antibody, zgc:110702 antibody, 2310011M22Rik antibody, 4930488F09Rik antibody, AW551873 antibody, Dph2l1 antibody, Ovca1 antibody, RGD1562694 antibody, diphthamide biosynthesis 1 antibody, diphthamide biosynthesis protein 1 antibody, diphthamide biosynthesis 1 L homeolog antibody, 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 antibody, DPH1 antibody, NCU08503 antibody, ATEG_01183 antibody, LELG_00973 antibody, HCAG_03806 antibody, AOR_1_728014 antibody, PTRG_05729 antibody, CTRG_01524 antibody, UREG_06411 antibody, BDBG_05574 antibody, MCYG_04396 antibody, PITG_12187 antibody, MGYG_02224 antibody, LOC100284663 antibody, dph1.L antibody, dph1 antibody, Dph1 antibody, dph-1 antibody

Background:

Synonyms: Candidate tumor suppressor in ovarian cancer 1, Diphthamide biosynthesis protein 1, Diphthamide biosynthesis protein 2 homolog like 1, Diphthamide biosynthesis protein 2 like, Diptheria toxin resistance protein required for diphthamide biosynthesis Saccharomyces like 1 , Diptheria toxin resistance protein required for diphthamide biosynthesis like 1, DPH like 1 S. cerevisiae, DPH like 1, DPH1, DPH1 homolog S. cerevisiae, DPH1 homolog, DPH2 like 1, DPH2L, DPH2L1, HsDph1, Ovarian cancer associated gene 1, Ovarian cancer associated gene 1 protein, Ovarian tumor suppressor candidate 1, DPH1_HUMAN.

Background: OVCA1 is required for the first step in the synthesis of diphthamide, a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. OVCA1 is one of several enzymes involved in synthesis of diphthamide in EEF2.

Gene ID: 1801