NME5 antibody (AA 81-150) (Biotin)

Catalog No. ABIN908531

Product Details anti-NME5 Antibody (Biotin)

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Binding Specificity: AA 81-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NME5 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NME5/IPIA beta

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NME5

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Alternative Name: NME5 (NME5 Products)

Synonyms: NM23-H5 antibody, NM23H5 antibody, RSPH23 antibody, 1700019D05Rik antibody, Nm23-M5 antibody, NME/NM23 family member 5 antibody, non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase) antibody, NME5 antibody, Nme5 antibody

Background:

Synonyms: Inhibitor of p53 induced apoptosis beta, IPIA beta, NDK-H 5, NDP kinase homolog 5, NM23 H5, Nm23-M5, NM23H5, Non-metastatic cells 5, protein expressed in nucleoside-diphosphate kinase, Nonmetastatic cells 5, protein expressed in, Nonmetastatic protein 23, homolog 5, Nucleoside diphosphate kinase homolog 5, RSPH23, Testis specic nm23 homolog, NDK5_HUMAN.

Background: NME5 does not seem to have NDK kinase activity but confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. It may play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. NME5 is specifically expressed in testis germinal cells.

Gene ID: 8382

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling