NEK1 antibody (AA 301-400) (HRP)

Catalog No. ABIN907933

Product Details anti-NEK1 Antibody (HRP)

Target: NEK1 (NIMA-Related Kinase 1 (NEK1))

Binding Specificity: AA 301-400

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEK1 antibody is conjugated to HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Sheep,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NEK1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NEK1

Target: NEK1 (NIMA-Related Kinase 1 (NEK1))

Alternative Name: NEK1 (NEK1 Products)

Synonyms: D8Ertd790e antibody, kat antibody, NY-REN-55 antibody, SRPS2 antibody, SRPS2A antibody, ATNEK1 antibody, F20D21.32 antibody, F20D21_32 antibody, NIMA-RELATED KINASE1 antibody, NIMA-related serine/threonine kinase 1 antibody, NIMA (never in mitosis gene a)-related expressed kinase 1 antibody, NIMA related kinase 1 antibody, NIMA-related kinase 1 antibody, NIMA-related serine/threonine kinase 1 antibody, Nek1 antibody, NEK1 antibody

Background:

Synonyms: SRPS2, SRTD6, SRPS2A, NY-REN-55, Serine/threonine-protein kinase Nek1, Never in mitosis A-related kinase 1, NimA-related protein kinase 1, Renal carcinoma antigen NY-REN-55, NEK1, KIAA1901

Background: Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Implicated in the control of meiosis (By similarity). Involved in cilium assembly. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death.

Gene ID: 4750

UniProt: Q96PY6