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NCKAP1 antibody (AA 1001-1132) (AbBy Fluor® 647)

NCKAP1 Reactivity: Mouse WB Host: Rabbit Polyclonal AbBy Fluor® 647
Catalog No. ABIN907761
  • Target See all NCKAP1 Antibodies
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1001-1132
    Reactivity
    • 33
    • 26
    • 11
    Mouse
    Host
    • 46
    • 1
    Rabbit
    Clonality
    • 47
    Polyclonal
    Conjugate
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NCKAP1 antibody is conjugated to AbBy Fluor® 647
    Application
    • 36
    • 18
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NCKAP1L
    Isotype
    IgG
    Top Product
    Discover our top product NCKAP1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    NCKAP1 (NCK Associated Protein 1 (NCKAP1))
    Alternative Name
    NCKAP1 (NCKAP1 Products)
    Synonyms
    HEM2 antibody, NAP1 antibody, NAP125 antibody, p125Nap1 antibody, C79304 antibody, H19 antibody, Hem-2 antibody, Hem2 antibody, Nap1 antibody, mKIAA0587 antibody, mh19 antibody, NCK associated protein 1 antibody, NCK-associated protein 1 antibody, NCK-associated protein 1 L homeolog antibody, NCKAP1 antibody, Nckap1 antibody, nckap1.L antibody
    Background

    Synonyms: NCK associated protein 1, NCK associated protein 1, Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, Nck-associated protein 1, Nckap1, NCKP1_HUMAN, p125Nap1.

    Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

    Gene ID
    10787
    UniProt
    P55160
    Pathways
    RTK Signaling, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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