MNAT1 antibody (AA 51-150) (AbBy Fluor® 488)
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- Target See all MNAT1 Antibodies
- MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))
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Binding Specificity
- AA 51-150
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MNAT1 antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Mouse, Rat
- Predicted Reactivity
- Human,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MNAT1
- Isotype
- IgG
- Top Product
- Discover our top product MNAT1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))
- Alternative Name
- MNAT1 (MNAT1 Products)
- Synonyms
- F6I18.270 antibody, F6I18_270 antibody, Afu4g08900 antibody, E130115E11Rik antibody, MAT1 antibody, P36 antibody, zgc:101599 antibody, CAP35 antibody, RNF66 antibody, TFB3 antibody, cyclin-dependent kinase-activating kinase assembly factor-related / CDK-activating kinase assembly factor-like protein antibody, CDK-activating kinase assembly factor MAT1 antibody, MNAT1, CDK activating kinase assembly factor antibody, menage a trois 1 antibody, MNAT CDK-activating kinase assembly factor 1 antibody, MNAT1, CDK activating kinase assembly factor L homeolog antibody, AT4G30820 antibody, AFUA_4G08900 antibody, NFIA_107260 antibody, CpipJ_CPIJ001565 antibody, AFLA_110530 antibody, BDBG_00548 antibody, TERG_06789 antibody, Tsp_08309 antibody, mnat1 antibody, Mnat1 antibody, MNAT1 antibody, mnat1.L antibody
- Background
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Synonyms: MAT1, TFB3, CAP35, RNF66, CDK-activating kinase assembly factor MAT1, CDK7/cyclin-H assembly factor, Cyclin-G1-interacting protein, Menage a trois, RING finger protein 66, RING finger protein MAT1, p35, p36, MNAT1
Background: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
- Gene ID
- 4331
- UniProt
- P51948
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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