Lamin B Receptor antibody (AA 1-100) (AbBy Fluor® 647)
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- Target See all Lamin B Receptor (LBR) Antibodies
- Lamin B Receptor (LBR)
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Binding Specificity
- AA 1-100
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Lamin B Receptor antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Specificity
- The immunogen for this product has partial sequence similarity to SEPT8 and SEPT2
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Cow,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Lamin B Receptor
- Isotype
- IgG
- Top Product
- Discover our top product LBR Primary Antibody
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- Application Notes
- FCM 1:20-100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Lamin B Receptor (LBR)
- Alternative Name
- Lamin B Receptor (LBR Products)
- Synonyms
- CG17952 antibody, Dmel\\CG17952 antibody, dLBR antibody, sb:cb406 antibody, zgc:86649 antibody, wu:fb75h08 antibody, wu:fc47b04 antibody, wu:fd36b07 antibody, lbr-A antibody, Xp58 antibody, p58 gene antibody, LBR antibody, DHCR14B antibody, LMN2R antibody, PHA antibody, TDRD18 antibody, AI505894 antibody, ic antibody, Nbp60 antibody, lamin B receptor antibody, Lamin B receptor antibody, lamin B receptor S homeolog antibody, LBR antibody, lbr antibody, lbr.S antibody, Lbr antibody
- Background
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Synonyms: PHA, LMN2R, TDRD18, DHCR14B, Lamin-B receptor, Integral nuclear envelope inner membrane protein, LBR
Background: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.
- Gene ID
- 3930
- UniProt
- Q14739
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