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KISS1R antibody (AA 139-157) (AbBy Fluor® 350)

KISS1R Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN903771
  • Target See all KISS1R Antibodies
    KISS1R (KISS1 Receptor (KISS1R))
    Binding Specificity
    • 11
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 139-157
    Reactivity
    • 46
    • 27
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 51
    • 1
    Rabbit
    Clonality
    • 51
    • 1
    Polyclonal
    Conjugate
    • 23
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KISS1R antibody is conjugated to AbBy Fluor® 350
    Application
    • 23
    • 13
    • 11
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Sheep,Pig,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KiSS1 receptor
    Isotype
    IgG
    Top Product
    Discover our top product KISS1R Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    KISS1R (KISS1 Receptor (KISS1R))
    Alternative Name
    Kiss1 Receptor (KISS1R Products)
    Synonyms
    AXOR12 antibody, CPPB1 antibody, GPR54 antibody, HH8 antibody, HOT7T175 antibody, KISS-1R antibody, Gpr54 antibody, KiSS-1 antibody, gpr54 antibody, gpr54-1 antibody, gpr54a antibody, kiss1r antibody, kiss1rl antibody, kissr2 antibody, si:dkey-31m5.9 antibody, axor12 antibody, kissr1a antibody, KISS1 receptor antibody, KISS1 receptor a antibody, KISS1R antibody, Kiss1r antibody, kiss1ra antibody, kiss1r antibody
    Background

    Synonyms: HH8, CPPB1, GPR54, AXOR12, KISS-1R, HOT7T175, KiSS-1 receptor, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor, KISS1R

    Background: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

    Gene ID
    84634
    UniProt
    Q969F8
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