KIF20A antibody (AA 353-450) (Biotin)

Catalog No. ABIN903684

Product Details anti-KIF20A Antibody (Biotin)

Target: KIF20A (Kinesin Family Member 20A (KIF20A))

Binding Specificity: AA 353-450

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIF20A antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KIF20A/MKLP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for KIF20A

Target: KIF20A (Kinesin Family Member 20A (KIF20A))

Alternative Name: MKLP2 (KIF20A Products)

Background:

Synonyms: MKLP2, RAB6KIFL, Kinesin-like protein KIF20A, GG10_2, Mitotic kinesin-like protein 2, Rab6-interacting kinesin-like protein, Rabkinesin-6, KIF20A

Background: Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.

Gene ID: 10112

UniProt: O95235