INSIG2 antibody (AA 65-160) (AbBy Fluor® 488)

Catalog No. ABIN902791

Product Details anti-INSIG2 Antibody (AbBy Fluor® 488)

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Binding Specificity: AA 65-160

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSIG2 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Insig2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for INSIG2

Target: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Alternative Name: Insig2 (INSIG2 Products)

Synonyms: MGC82156 antibody, INSIG-2 antibody, 2900053I11Rik antibody, C730043J18Rik antibody, Insig-2 antibody, insulin induced gene 2 antibody, insulin induced gene 2 L homeolog antibody, insig2 antibody, insig2.L antibody, INSIG2 antibody, Insig2 antibody

Background:

Synonyms: Hypothetical protein INSIG2, INSIG 2, INSIG-2, INSIG 2 membrane protein, INSIG2 membrane protein, Insulin induced gene 2, Insulin induced gene 2 protein, Insulin induced protein 2, MGC26273, INSI2_HUMAN.

Background: Insig2 is highly similar to the protein product encoded by gene Insig1. Both Insig1 protein and Insig2 protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Gene ID: 51141

Pathways: ER-Nucleus Signaling