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IER3 antibody (AA 85-156) (AbBy Fluor® 555)

IER3 Reactivity: Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 555
Catalog No. ABIN901742
  • Target See all IER3 Antibodies
    IER3 (Immediate Early Response 3 (IER3))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    AA 85-156
    Reactivity
    • 33
    • 18
    • 15
    • 4
    • 4
    • 4
    Rat
    Host
    • 47
    Rabbit
    Clonality
    • 47
    Polyclonal
    Conjugate
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IER3 antibody is conjugated to AbBy Fluor® 555
    Application
    • 36
    • 20
    • 14
    • 14
    • 13
    • 12
    • 12
    • 6
    • 6
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IEX1/Differentiation dependent gene 2 protein
    Isotype
    IgG
    Top Product
    Discover our top product IER3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IER3 (Immediate Early Response 3 (IER3))
    Alternative Name
    IEX1 (IER3 Products)
    Synonyms
    DIF-2 antibody, DIF2 antibody, GLY96 antibody, IEX-1 antibody, IEX-1L antibody, IEX1 antibody, PRG1 antibody, AI663993 antibody, cI-3 antibody, gly96 antibody, IER3 antibody, Dif2 antibody, Iex1 antibody, Ler3 antibody, Prg1 antibody, immediate early response 3 antibody, IER3 antibody, Ier3 antibody
    Background

    Synonyms: DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, Radiation-inducible immediate-early gene IEX-1, Differentiation-dependent gene 2 protein, Protein DIF-2, Immediate early protein GLY96, Immediate early response 3 protein, PACAP-responsive gene 1 protein, Protein PRG1, IER3

    Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

    Gene ID
    8870
    UniProt
    P46695
    Pathways
    Regulation of Carbohydrate Metabolic Process
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