HRPT2 antibody (AA 61-160) (AbBy Fluor® 488)

Catalog No. ABIN901338

Product Details anti-HRPT2 Antibody (AbBy Fluor® 488)

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Binding Specificity: AA 61-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRPT2 antibody is conjugated to AbBy Fluor® 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HRPT2/Parafibromin

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Alternative Name: Parafibromin (CDC73 Products)

Synonyms: C1orf28 antibody, HPTJT antibody, HRPT2 antibody, HYX antibody, 8430414L16Rik antibody, BC027756 antibody, C130030P16Rik antibody, C81219 antibody, Hrpt2 antibody, hrpt2 antibody, zgc:63956 antibody, MGC108428 antibody, cdc73 antibody, LOC100222932 antibody, cell division cycle 73 antibody, cell division cycle 73, Paf1/RNA polymerase II complex component antibody, cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) antibody, parafibromin antibody, cell division cycle 73 S homeolog antibody, CDC73 antibody, Cdc73 antibody, cdc73 antibody, Tsp_03925 antibody, Tsp_04052 antibody, Tsp_04125 antibody, cdc73.S antibody

Background:

Synonyms: C1orf28,CDC 73,CDC73,Cell division cycle 73,Cell division cycle 73 Paf1/RNA polymerase II complex component homolog,Cell division cycle protein 73 homolog,FLJ23316,HPT-JT,HRPT 2,Hyperparathyroidism 2 with jaw tumor,Hyperparathyroidism 2,Hyperparathyroidism 2 protein,Parafibromin.

Background: The HRPT2 gene product, parafibromin, is a tumor suppressor protein that is part of the human Paf1 complex. The yeast counterpart to this complex is part of the RNA polymerase II complex as well, and is important for histone modification and connections to posttranscriptional events. Human parafibromin also associates with the RNA polymerase II large subunit.

Gene ID: 79577

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance