HRPT2 antibody (AA 61-160) (HRP)

Catalog No. ABIN901328

Product Details anti-HRPT2 Antibody (HRP)

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Binding Specificity: AA 61-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRPT2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HRPT2/Parafibromin

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Alternative Name: Parafibromin (CDC73 Products)

Background:

Synonyms: C1orf28,CDC 73,CDC73,Cell division cycle 73,Cell division cycle 73 Paf1/RNA polymerase II complex component homolog,Cell division cycle protein 73 homolog,FLJ23316,HPT-JT,HRPT 2,Hyperparathyroidism 2 with jaw tumor,Hyperparathyroidism 2,Hyperparathyroidism 2 protein,Parafibromin.

Background: The HRPT2 gene product, parafibromin, is a tumor suppressor protein that is part of the human Paf1 complex. The yeast counterpart to this complex is part of the RNA polymerase II complex as well, and is important for histone modification and connections to posttranscriptional events. Human parafibromin also associates with the RNA polymerase II large subunit.

Gene ID: 79577

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance