SPINT1 antibody (AA 451-529) (AbBy Fluor® 647)
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- Target See all SPINT1 Antibodies
- SPINT1 (serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1))
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Binding Specificity
- AA 451-529
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SPINT1 antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HAI-1
- Isotype
- IgG
- Top Product
- Discover our top product SPINT1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SPINT1 (serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1))
- Alternative Name
- HAI-1 (SPINT1 Products)
- Synonyms
- HAI-1 antibody, HAI antibody, HAI1 antibody, MANSC2 antibody, cb376 antibody, sb:cb376 antibody, spint1l antibody, zgc:64075 antibody, serine peptidase inhibitor, Kunitz type 1 antibody, serine protease inhibitor, Kunitz type 1 antibody, serine peptidase inhibitor, Kunitz type 1 b antibody, serine peptidase inhibitor, Kunitz type 1 a antibody, SPINT1 antibody, Spint1 antibody, spint1b antibody, spint1a antibody
- Background
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Synonyms: Hepatocyte Growth Factor Activator Inhibitor 1, Spint1, Hai1, HGFA Inhibitor 1, HAI-1, SPIT1_HUMAN.
Background: HGFA Inhibitor 1 is an endogenous inhibitor of the kunitz-type serine proteinase HGF-activator (HGFA). HGF was first described as a hepatocyte-specific mitogen and survival factor, and has since been shown to exert a variety of actions on many cell types by binding to its MET receptor. HGF is activated by cleavage of the single-chain form to form a two-chain version by HGFA. HGFA Inhibitor 1 also inhibits trypsin, and MTSP-1 (Matriptase), a serine proteinase that also activates HGF. HGFB Inhibitor 1 is a splice variant of HGFA Inhibitor 1, and contains a 16 amino acid insert after the first kringle domain, relative to the HGFA Inhibitor 1 sequence.
- Gene ID
- 6692
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