Glutathione Reductase antibody (AA 421-522) (AbBy Fluor® 350)
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- Target See all Glutathione Reductase (GSR) Antibodies
- Glutathione Reductase (GSR)
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Binding Specificity
- AA 421-522
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Glutathione Reductase antibody is conjugated to AbBy Fluor® 350
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GSR
- Isotype
- IgG
- Top Product
- Discover our top product GSR Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- Glutathione Reductase (GSR)
- Alternative Name
- GLUR/glutathione reductase (GSR Products)
- Synonyms
- GR antibody, ATGR2 antibody, EMB2360 antibody, glutathione reductase antibody, AI325518 antibody, D8Ertd238e antibody, Gr-1 antibody, Gr1 antibody, DDBDRAFT_0168952 antibody, DDBDRAFT_0231410 antibody, DDB_0168952 antibody, DDB_0231410 antibody, 2151 antibody, CG2151 antibody, DTR antibody, Dm-TrxR antibody, DmTR antibody, DmTrx antibody, DmTrxR antibody, DmTrxR-1 antibody, Dmel\\CG2151 antibody, Gr antibody, Trx antibody, TrxR antibody, TrxR-1 antibody, Trxr1 antibody, anon-WO03040301.185 antibody, anon-WO03040301.187 antibody, dTrxR antibody, dmtrxr-1 antibody, gr antibody, l(1)G0154 antibody, l(1)G0379 antibody, l(1)G0477 antibody, l(1)G0481 antibody, trxr-1 antibody, gor1 antibody, glutathione reductase, gro-2 antibody, glutathione reductase antibody, glutathione-disulfide reductase antibody, GR; GRase antibody, mitochondrial glutathione reductase Pgr1 antibody, Glutathione reductase (GR) (GRase) antibody, Thioredoxin reductase-1 antibody, glutathione-disulfide reductase family protein antibody, glutathione reductase 1 antibody, GR antibody, gor antibody, GSR antibody, GSR1 antibody, Gsr_2 antibody, Gsr antibody, GSHR1 antibody, gsr antibody, LbGR antibody, pgr1 antibody, GSHR2 antibody, GLR2 antibody, Bcen_2392 antibody, RPE_1989 antibody, HCAG_02219 antibody, SJAG_01162 antibody, Trxr-1 antibody, PF14_0192 antibody, POPTR_0001s14480g antibody, gsr1 antibody
- Background
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Synonyms: glutathione reductase, GLUR, Glutathione reductase mitochondrial, GR, Gr1, GRase, GRD 1, GRD1, GSR, MGC78522.
Background: Glutathione reductase (GR) is a member of pyridine nucleotide- disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+?2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.
- Gene ID
- 2890
- Pathways
- Thyroid Hormone Synthesis, Cell RedoxHomeostasis
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