GIMAP8 antibody (AA 551-565) (Biotin)

Catalog No. ABIN898930

Product Details anti-GIMAP8 Antibody (Biotin)

Target: GIMAP8 (GTPase, IMAP Family Member 8 (GIMAP8))

Binding Specificity: AA 551-565

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIMAP8 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GIMAP8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GIMAP8

Target: GIMAP8 (GTPase, IMAP Family Member 8 (GIMAP8))

Alternative Name: GIMAP8 (GIMAP8 Products)

Synonyms: IAN-9 antibody, IAN6 antibody, IANT antibody, hIAN6 antibody, Gm457 antibody, IAN9 antibody, IMAP8 antibody, IanT antibody, GTPase, IMAP family member 8 antibody, GIMAP8 antibody, Gimap8 antibody

Background:

Synonyms: GTPase IMAP family member 8, hIAN6, Human immune associated nucleotide 6, IAN9, IANT, Immune associated nucleotide, Immune-associated nucleotide-binding protein 9, Protein IanT, GIMA8_HUMAN.

Background: The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP8, also known as IAN9 (immune-associated nucleotide-binding protein 9) or IANT, is a 665 amino acid protein that localizes to Golgi apparatus, Endoplasmic reticulum and mitochondria. Suggested to have an anti-apoptotic effect on the immune system, GIMAP8 plays a role in infection response and is encoded by a gene that maps to human chromosome 7q36.1. Chromosome 7 houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Gene ID: 155038

UniProt: Q8ND71