GCKR antibody (AA 121-220) (Biotin)
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- Target See all GCKR Antibodies
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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Binding Specificity
- AA 121-220
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GCKR antibody is conjugated to Biotin
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GCKR
- Isotype
- IgG
- Top Product
- Discover our top product GCKR Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Alternative Name
- Glucokinase regulatory protein (GCKR Products)
- Synonyms
- FGQTL5 antibody, GKRP antibody, GLRE antibody, gckr antibody, glucokinase regulator antibody, glucokinase regulatory protein antibody, glucokinase regulator L homeolog antibody, GCKR antibody, Gckr antibody, gckr.L antibody
- Background
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Synonyms: GKRP, FGQTL5, Glucokinase regulatory protein, Glucokinase regulator, GCKR
Background: Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
- Gene ID
- 2646
- UniProt
- Q14397
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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