UBR1 antibody (AA 801-900) (AbBy Fluor® 647)
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- Target See all UBR1 Antibodies
- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
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Binding Specificity
- AA 801-900
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UBR1 antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human eIF3A
- Isotype
- IgG
- Top Product
- Discover our top product UBR1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
- Alternative Name
- e3A (UBR1 Products)
- Synonyms
- Dmel\\CG9086 antibody, Ubr1 antibody, UBR1 antibody, JBS antibody, AI504731 antibody, RGD1562326 antibody, Ubr1 ubiquitin ligase antibody, ubiquitin protein ligase E3 component n-recognin 1 antibody, E3 ubiquitin-protein ligase ubr-1 antibody, Ubr1 antibody, ubr1 antibody, UBR1 antibody, ubr-1 antibody
- Background
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Synonyms: EIF3, P167, p180, p185, TIF32, EIF3S10, eIF3-p170, eIF3-theta, Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10, eIF-3-theta, eIF3 p167, eIF3 p180, eIF3 p185, KIAA0139
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
- Gene ID
- 8661
- UniProt
- Q14152
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